In vitro oxidative stress regulatory potential of Citrullus colocynthis and Tephrosia apollinea-Reference-Cited by-同舟云学术

In vitro oxidative stress regulatory potential of Citrullus colocynthis and Tephrosia apollinea

Published:2018-04-26 Issue:2 Volume:68 Page:235-242
ISSN:1846-9558
Container-title:Acta Pharmaceutica
language:en
Short-container-title:

Author:

Rizvi Tania Shamim¹,Khan Abdul Latif¹,Ali Liaqat¹²,Al-Mawali Narjis¹,Mabood Fazal³,Hussain Javid³,Adnan Muhammad⁴,Al-Harrasi Ahmed¹³

Affiliation:

1. UoN Chair of Oman’s Medicinal Plants and Marine Natural Products , University of Nizwa , Birkat Al-Mouz, Nizwa - 616 , Oman

2. Department of Chemistry , University of Sargodha , Pakistan

3. Department of Biological Science and Chemistry , University of Nizwa , Birkat Al-Mouz, Nizwa - 616 , Oman

4. Department of Botany , Kohat University of Science and Technology , Kohat - 26000 , Pakistan

Abstract

Abstract The present study investigates the potential role of medicinal plants Citrullus colocynthis and Tephrosia apollinea in ameliorating the oxidative stress developed during the generation of reactive oxygen species. Organic extracts of different organs (leaf, stem and root) of these medicinal plants obtained in n-hexane, chloroform, n-butanol and water were assayed for radical scavenging, total antioxidant capacity, anti-lipid peroxidation and reduced glutathione. The total phenolic content (TPC) of both selected medicinal plants was also evaluated. The results indicated that extracts of T. apollinea leaf, stem and root have higher TPC compared to those of C. colocynthis. Similarly, the results of the present study revealed higher bioactivity of C. colocynthis than that of T. apollinea in various antioxidant assays. Various plant parts of each plant were also compared.

Publisher

Walter de Gruyter GmbH

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Link

https://www.sciendo.com/pdf/10.2478/acph-2018-0012

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