Preparation of α-damascone-Reference-Cited by-同舟云学术

Preparation of α-damascone

Published:2019-03-01 Issue:1 Volume:21 Page:50-51
ISSN:1899-4741
Container-title:Polish Journal of Chemical Technology
language:en
Short-container-title:

Author:

Hu Junyi¹,Guo Aiqiang¹,Xu Yingqian¹,Pan Changsheng²,Wei Xingfu¹,Wang Longlong¹,Xiao Guoyong¹

Affiliation:

1. University of Science and Technology Liaoning , School of Chemical Engineering , Liaoning Anshan , 114051 , P. R. China

2. Jijia Geen Bilding Tchnology co., LTD, Liaoning Anshan , 114051 , P. R. China

Abstract

Abstract α-Damascone is widely used in perfumes. However, the manufacture of α-damascone remains challenging owing to the limitations of current production processes. Herein, α-damascone was successfully synthesized from α-ionone using a new route involving only four steps, namely oximization, epoxidation, dehydration, and reduction. The total yield was 54.9% with a final chemical purity of 97% (by GC). Only water, cyclohexane, and ethanol were used in the reactions except in the purification step, and all solvents could be recycled. The structures of the intermediates and target compound were identified by 1H NMR and 13C NMR analyses and MS experiments. This route is a simple and successful method for the industrial preparation of α-damascone.

Publisher

Walter de Gruyter GmbH

Subject

General Chemical Engineering,General Chemistry,Biotechnology

Link

https://www.sciendo.com/pdf/10.2478/pjct-2019-0009

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