Garlic the Wonder Adjuvant in Medicinal Field

Abstract

Abstract Background: Plant derived compounds are drawing attention in curing and treating variety of ailment and diseases. This increase in popularity of natural products has renewed interest in garlic, which has been used by human for centuries. It has been found that garlic pulp contains more than 200 chemical compounds and numerous garlic molecules can still be explored, extracted, synthesized and optimized. As in market various preparations of garlic are available which include tablets made from dried and powdered clove, oils and liquid extracts however, it would also be interesting to explore the effect of different forms of garlic extract on standard drug therapy especially when used as an adjuvant therapy. In this review a report on the pharmaceutical preparation which has used extracted compounds from garlic or its derivatives as a main constituent is compiled, so that it could be useful to increase our knowledge about the therapeutic effect of garlic and could improve our future experimental and chemical plans. Methods: We performed a systematic review of literature using term garlic. Result: In this report a comprehensive investigation has been conducted on garlic which includes various scientific aspects about it by which researchers from various disciplines could be directed to put efforts toward discovering the benefits of garlic on human health. Conclusion: Garlic and its extracts had a wide range of applications even against resistant organisms to serve as powerful anti-microbial agent. Therefore, research is needed to refine the pathophysiological mechanisms of action of garlic and its utility in treatment of various diseases by developing more stable and suitable formulations. The development of Garlic as a commercial anti-biotic has come to a halt. Although its efficiency is scientifically proven still it has only been used as dietary supplement or as traditional medicine.