Experimental Animal Models of Periodontal Diseases-Reference-Cited by-同舟云学术

Experimental Animal Models of Periodontal Diseases

Published:2024-05-01 Issue:0 Volume:0 Page:
ISSN:2956-2090
Container-title:Experimental and Applied Biomedical Research (EABR)
language:en
Short-container-title:

Author:

Velickovic Milica¹,Acovic Aleksandar¹,Arsenijevic Aleksandar²,Milovanovic Jelena²³,Rakic Mia⁴,Milovanovic Marija²,Kanjevac Tatjana¹,Arsenijevic Dragana⁵

Affiliation:

1. University of Kragujevac, Faculty of Medical Sciences , Department of Dentistry , Kragujevac , Serbia

2. Center for Molecular Medicine and Stem Cell Research, Faculty of Medical Sciences , University of Kragujevac , Kragujevac , Serbia

3. Department of Histology and Embriology, Faculty of Medical Sciences , University of Kragujevac , Kragujevac , Serbia

4. ETEP (Etiology and Therapy of Periodontal Diseases) Research Group, Faculty of Dentistry , University Complutense of Madrid , Pza. Ramón y Cajal, s/n, Madrid , Spain

5. Department of Pharmacy, Faculty of Medical Sciences , University of Kragujevac , Kragujevac , Serbia

Abstract

Abstract Periodontal diseases involve several conditions that are defined by pathologic loss of the periodontal ligament and alveolar bone. Periodontitis is an inflammatory disease of periodontal tissue caused by a host immune response to dysbiotic microbial biofilm whose progression associated with destruction of tooth supporting tissue is promoted by host proteinases. Periradicular periodontitis is the most commonly diagnosed disease that affects the pathology of periodontal tissue in the area of the tooth root. This disease has also been described as apical periodontitis. Several experimental models of periodontal diseases have been developed in recent years. This paper provides an overview of experimentally induced animal models of periodontal disease (periodontitis and periradicular periodontitis) and the possibility of using different experimental animals to study aspects of periodontal disease, each with advantages and disadvantage.

Publisher

Walter de Gruyter GmbH

Link

https://www.sciendo.com/pdf/10.2478/sjecr-2021-0019

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