Cholinergic syndrome: a case report of acute organophosphate and carbamate poisoning-Reference-Cited by-同舟云学术

Cholinergic syndrome: a case report of acute organophosphate and carbamate poisoning

Published:2020-06-01 Issue:2 Volume:71 Page:163-166
ISSN:1848-6312
Container-title:Archives of Industrial Hygiene and Toxicology
language:en
Short-container-title:

Author:

Petreski Tadej¹²,Kit Barbara³,Strnad Matej²⁴,Grenc Damjan⁵,Svenšek Franc³

Affiliation:

1. University Medical Centre Maribor, Clinic for Internal Medicine , Department of Nephrology , Maribor , Slovenia

2. University of Maribor , Faculty of Medicine , Maribor , Slovenia

3. University Medical Centre Maribor , Clinic for Internal Medicine, Intensive Care Unit , Maribor , Slovenia

4. Centre for Emergency Medicine, Prehospital Unit , Maribor , Slovenia

5. University Medical Centre Ljubljana , Clinic for Internal Medicine, Centre for Clinical Toxicology and Pharmacology , Ljubljana , Slovenia

Abstract

Abstract Cholinergic syndrome is a common topic at western medical universities yet rarely observed in clinical practice. The treatment involves muscarinic antagonists, acetylcholinesterase reactivation, seizure control, and supportive measures. Here we report a case of a 52-year old Caucasian male who attempted suicide by ingesting a purple crystal powder that turned out to be a mixture of carbofuran and chlormephos. At clinical examination, the patient presented with salivation, perspiration, diarrhoea, bradypnoea, loss of consciousness, and epileptic seizures. Laboratory tests showed low plasma cholinesterase, and we started obidoxime along with supportive intensive care treatment. He was later transferred to the psychiatry department for further diagnostics and treatment.

Publisher

Walter de Gruyter GmbH

Subject

Public Health, Environmental and Occupational Health,Toxicology

Link

https://www.sciendo.com/pdf/10.2478/aiht-2020-71-3413

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