Affiliation:
1. 1Institute of Organic Chemistry, Lodz University of Technology, 90-924, Lodz, Poland
2. 2Institute of General and Environmental Chemistry, Lodz University of Technology, 90-924, Lodz, Poland
Abstract
AbstractTertiary phosphines in reaction with 2-chloro-4,6-dialkoxy-1,3,5-triazines gave unstable quaternary P-triazinylphosphonium chlorides, which readily decomposed with a departure of the alkyl group of the triazine ring substituent. Stable quaternary P-triazinylphosphonium chlorides were obtained only in reaction of 2-chloro-4,6-diphenoxy-1,3,5-triazine. Both, stable quaternary P-triazinylphosphonium chlorides as well unstable analogues prepared in situ activated carboxylic acid yielding “superactive” triazine esters, useful as highly efficient reagents in peptide bond synthesis.
Subject
Materials Chemistry,General Chemistry
Reference28 articles.
1. http dx org;Kamiński;Prakt Chem,1990
2. http dx org;Faham;Chem Rev,2011
3. http dx org;Lee;Phys Org Chem,1994
4. chemistry design and synthesis of peptides conformational analysis and biological functions and references cited therein;Hruby;Peptide,1998
5. The effect of solvents on the selectivity of electrophilic reagents. I. Radical halogenation of substituted toluenes
Cited by
3 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献