Affiliation:
1. University of Medicine, Pharmacy, Science and Technology of Târgu Mureș , Department of Pharmaceutical Chemistry
Abstract
Abstract
Triptans are specific drugs for migraine attack, their use leads to selective vasoconstriction, while the inflammatory condition that usually occurs during migraine is reduced. The structurally indolamine derivatives are selective agonists of the serotonin 1B/1D receptor. This review presents the history, representatives, production, and physico-chemical properties of triptans, but also discusses their pharmacological properties and mechanism of action.