Affiliation:
1. Department of Poultry Diseases, Faculty of Veterinary Medicine, University of Warmia and Mazury , Olsztyn , Poland
Abstract
Abstract
Introduction
Turkey histomonosis poses a serious threat to poultry production due to the ban on the use of effective drugs. The aim of the study was to evaluate the influence of a phytoncidal feed supplement on the course of histomonosis. The preparation was also analysed for immunomodulatory properties.
Material and Methods
Clinical observations and production monitoring were conducted in a flock of turkeys with histomonosis from their 11th to 56th weeks of life which were treated with the adiCoxSOLPF soluble supplement in a dose of 2.5 mL/L water. Later the preparation was used in a preventive dose (1 mL/L). The influence on the immune system was evaluated in broiler turkeys having been given adiCoxSOLPF for 3 days in doses of 1 or 3 mL/L. The T and B lymphocyte percentages in turkey blood and spleen tissue were analysed with flow cytometry. ELISA was implemented to evaluate antibody titres after Ornithobacterium rhinotracheale vaccination, and biochemical analyses were performed to evaluate the supplement’s safety.
Results
AdiCoxSOLPF was found effective in therapy and prevention of histomonosis. Additionally, adiCoxSOLPF stimulated both humoral and cell-mediated immune mechanisms, without impairing the functions of internal organs. The treated turkeys also yielded better production results (eggs/hen, fertility, and hatchability).
Conclusion
AdiCoxSOLPF possesses immunomodulatory properties and it can be used successfully in the prevention and therapy of histomonosis in turkeys.
Reference33 articles.
1. Arshad N., Zitterl-Eglseer K., Hasnain S., Hess M.: Effect of Peganum harmala or its beta-carboline alkaloids on certain antibiotic resistant strains of bacteria and protozoa from poultry. Phytother Res 2008, 22, 1533–1538, doi: 10.1002/ptr.2528.
2. Baynes R.E., Dedonder K., Kissell L., Mzyk D., Marmulak T., Smith G., Tell L., Gehring R., Davis J., Riviere J.E.: Health concerns and management of select veterinary drug residues. Food Chem Toxicol 2016, 88, 112–122, doi: 10.1016/j.fct.2015.12.020.
3. Bobusia K.: Epizootic situation of histomonosis in broilers breeders flocks and turkeys flocks from selected areas of Poland and evaluation of diagnostic methods used to identify Histomonas meleagridis PhD thesis, University of Life Sciences, Wrocław 2015.
4. Clark S., Kimminau E.: Critical review: Future control of blackhead disease (histomoniasis) in poultry. Avian Dis 2017, 61, 281–288, doi: 0.1637/11593-012517-ReviewR.
5. Codex Alimentarius Commission: Report of the twenty-second session of the Codex Committee on Residues of Veterinary Drugs in Foods. San Jose, Costa Rica, 2015.
Cited by
4 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献