Affiliation:
1. Department of Internal Medicine and Oncological Chemotherapy , Medical University of Silesia Katowice 40-027 , Poland
Abstract
Abstract
Substances available in nature with potential therapeutic effects are the subject of research that raises tremendous hopes for new challenges in medicine. Fungi are the most common organisms in the ecosystem and the most interesting in this respect. This review discusses two species of edible fungi, used for centuries in Eastern natural medicine, with the best-documented effect – Hericium erinaceus (He) and Trametes versicolor (Tv). The results of in vivo and in vitro studies conducted on mice and human cell lines demonstrate immunomodulatory, potentially, anticancer, anti-inflammatory and neuroregenerative effects of substances isolated from these fungi. The substances contained in the extracts of He and Tv seem to have immunomodulatory effects that may support chemotherapy. The use of these extracts is justified stronger than the other supportive treat ments based on supplements.
Subject
Pharmaceutical Science,Pharmacology,General Medicine
Reference61 articles.
1. 1. W. Sneader, Drug Discovery. A History, John Wiley & Sons, Chichester 2005.10.1002/0470015535
2. 2. D. T. Courtwright, Forces of Habit – Drugs and the Making of the Modern World, Harvard University Press, Cambridge (MA) 2002.
3. 3. M. Hanada, Case Studies in Modern Drug Discovery and Development, John Wiley & Sons, Hoboken (NJ) 2012.
4. 4. D. A. Dias, S. Urban and U. Roessner, A historical overview of natural products in drug discovery, Metabolites2 (2012) 303–336; https://doi.org/10.3390/metabo202030310.3390/metabo2020303
5. 5. M. Friedman, Chemistry, nutrition, and health-promoting properties of Hericium erinaceus (Lion’s mane) mushroom fruiting bodies and mycelia and their bioactive compounds, J. Agric. Food Chem. 63 (2015) 7108–7123; https://doi.org/10.1021/acs.jafc.5b0291410.1021/acs.jafc.5b02914
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