Endocrine changes in women with a medically indicated abortion: the study design

Author:

Romanova Zuzana12,Kornanova Eva3,Garafova Alexandra41,Borovsky Miroslav3,Jezova Daniela1

Affiliation:

1. Slovak Academy of Sciences, Biomedical Research Center , Institute of Experimental Endocrinology

2. Comenius University Bratislava , Faculty of Pharmacy, Department of Pharmacology and Toxicology

3. Comenius University Bratislava , Faculty of Medicine, 1st Department of Obstetrics and Gynaecology , University Hospital Bratislava

4. Slovak Medical University , Faculty of Medicine, Department of Neonatology , University Hospital Bratislava , Bratislava , Slovakia

Abstract

Abstract A strongly psychosocially demanding situation in the life of a woman is the option of medically indicated abortion. Here we present the design of an ongoing study aiming to examine the stressfulness of life events related to medically indicated abortions by measuring cortisol concentrations in the participants’ hair and saliva. Pilot results show high salivary cortisol concentrations in the majority of the women one day before induced abortion. In half of the group, two months after the abortion, hair cortisol concentrations were higher in comparison to cumulative values from two months before. There were no changes in the second half.

Publisher

Walter de Gruyter GmbH

Subject

General Pharmacology, Toxicology and Pharmaceutics

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