Immunological and pathological investigations of non-specific reactive hepatitis in shelter dogs-Reference-Cited by-同舟云学术

Immunological and pathological investigations of non-specific reactive hepatitis in shelter dogs

Published:2019-03-01 Issue:1 Volume:69 Page:61-72
ISSN:1820-7448
Container-title:Acta Veterinaria
language:en
Short-container-title:

Author:

Jaber Jose Raduan¹,Velázquez-Wallraf Alicia S¹,Farray David¹,Ravelo-García Antonio G.²,Carrascosa Conrado¹,Rodríguez-Ventura Myriam¹,Perez Jose³

Affiliation:

1. Department of Morphology, Veterinary Faculty , University of Las Palmas de Gran Canaria

2. Institute for Technological Development and Innovation in Communications , University of Las Palmas de Gran Canaria

3. Department of Anatomía y Anatomía Patológica Comparada , Veterinary College , University of Cordoba

Abstract

Abstract The aim of this study was to describe the gross, histopathological and immunohistochemical features of non-specific reactive hepatitis (NSRH) in stray dogs. To perform this study the livers of 23 dogs of different breed and sex were used. The tissue sections were stained with hematoxylin–eosin, and immunohistochemically. The results of this work showed that NSRH was characterized by the infiltration of lymphocytes and plasma cells scattered throughout the liver parenchyma and in the portal stroma, and associated with inflammatory and non-inflammatory diseases in other organ systems. The inflammatory infiltrate of NSRH was composed of CD3+ T lymphocytes and HLA-DR+ lymphocytes, as well as IgG+ plasma cells and alpha-1-antitrypsin+ macrophages in the portal spaces and hepatic sinusoids.

Publisher

Walter de Gruyter GmbH

Subject

General Veterinary

Link

https://www.sciendo.com/pdf/10.2478/acve-2019-0004

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