Predictive value of lymphocyte-to-monocyte ratio in patients with contrast-induced nephropathy after percutaneous coronary intervention for acute coronary syndrome-Reference-Cited by-同舟云学术

Predictive value of lymphocyte-to-monocyte ratio in patients with contrast-induced nephropathy after percutaneous coronary intervention for acute coronary syndrome

Published:2020-06-01 Issue:2 Volume:9 Page:123-130
ISSN:2224-4018
Container-title:Journal of Translational Internal Medicine
language:en
Short-container-title:

Author:

Karauzum Irem¹,Karauzum Kurtulus¹,Acar Burak¹,Hanci Kaan¹,Bildirici Halil ibrahim Ulas²,Kilic Teoman¹,Ural Ertan¹

Affiliation:

1. Kocaeli University Faculty of Medicine , Istanbul , Turkey

2. Department of Cardiology , Biruni University , Istanbul , Turkey

Abstract

Abstract Background and Objectives Lymphocyte-to-monocyte ratio (LMR) has emerged as a new indirect marker of inflammation, which is associated with adverse outcomes in cardiovascular diseases. The aim of this study was to evaluate whether admission LMR is associated with contrast-induced nephropathy (CIN) in patients who underwent percutaneous coronary intervention for acute coronary syndrome (ACS). Methods A total of 873 patients were assessed. LMR was calculated via dividing lymphocyte count by monocyte count. Results LMR was significantly lower in the with-CIN group. ROC analysis showed that the LMR ratios <2.52 predicted CIN development with sensitivity of 66.3% and specificity of 55.8%. Multivariate analysis showed that eGFR, admission glucose, and LMR were independent predictors of CIN in patients with ACS. Conclusion LMR is an easily accessible marker and could be used as a predictor of CIN in patients with ACS undergoing percutaneous coronary intervention.

Publisher

Walter de Gruyter GmbH

Link

https://www.sciendo.com/pdf/10.2478/jtim-2021-0024

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