Affiliation:
1. Department of Electrophysiology, Heart Center Leipzig , Germany
Abstract
Abstract
Atrial fibrillation (AF), as the most common cardiac arrhythmia worldwide, is associated with increased mortality and morbidity. Successful therapeutic strategies have been introduced so far, but they are associated with significant costs. Therefore, identification of modifiable risk factors of AF and the development of appropriate preventive strategies may play a substantial role in promoting community health and reducing health care system costs. Modifiable cardiovascular risk factors including obesity, hypertension, diabetes mellitus, obstructive sleep apnea, alcohol consumption, smoking, and sedentary lifestyles have been proposed as possible contributors to the development and progression of AF. In this review, we discuss the role of modifiable risk factors in the development and management of AF and the evidence for the underlying mechanism for each of the potential risk factor.
Reference93 articles.
1. 1. KIRCHHOF P, BREITHARDT G, BAX J, BENNINGER G, BLOMSTROM-LUNDQVIST C, BORIANI G et al. A roadmap to improve the quality of atrial fibrillation management: Proceedings from the fifth Atrial Fibrillation Network/European Heart Rhythm Association consensus conference. Europace: European pacing, arrhythmias, and cardiac electrophysiology. Journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 2016;18(1):37-50. doi:10.1093/europace/euv304.10.1093/europace/euv304
2. 2. HONG KL, GLOVER BM. The impact of lifestyle intervention on atrial fibrillation. Current opinion in cardiology. 2018;33(1):14-9.
3. 3. RAATIKAINEN MJ, ARNAR DO, MERKELY B, CAMM AJ, HINDRICKS G. Access to and clinical use of cardiac implantable electronic devices and interventional electrophysiological procedures in the European Society of Cardiology Countries: 2016 Report from the European Heart Rhythm Association. Europace: European pacing, arrhythmias, and cardiac electrophysiology. Journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 2016;18 Suppl 3:iii1-iii79. doi:10.1093/europace/euw244.10.1093/europace/euw244
4. 4. RAATIKAINEN MJP, ARNAR DO, MERKELY B, NIELSEN JC, HINDRICKS G, HEIDBUCHEL H et al. A Decade of information on the use of cardiac implantable electronic devices and interventional electrophysiological procedures in the European Society of Cardiology Countries: 2017 Report from the European Heart Rhythm Association. Europace: European pacing, arrhythmias, and cardiac electrophysiology. Journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 2017;19(suppl_2):ii1-ii90. doi:10.1093/europace/eux258.10.1093/europace/eux258
5. 5. GARDARSDOTTIR M, SIGURDSSON S, ASPELUND T, ROKITA H, LAUNER LJ, GUDNASON V et al. Atrial fibrillation is associated with decreased total cerebral blood flow and brain perfusion. Europace: European pacing, arrhythmias, and cardiac electrophysiology. Journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 2017. doi:10.1093/europace/eux220.10.1093/europace/eux220