Monitoring Tissue Oxygen Saturation in Microgravity on Parabolic Flights

Author:

Smith Thomas G.1,Formenti Federico12,Hodkinson Peter D.13,Khpal Muska14,Mackenwells Brian P.15,Talbot Nick P.16

Affiliation:

1. Aerospace Medicine Research Group , University of Oxford , Oxford , UK

2. Centre of Human and Aerospace Physiological Sciences , King's College London , London , UK

3. Royal Air Force Centre of Aviation Medicine , RAF Henlow, UK

4. Anaesthetics Department , University College Hospital , London , UK

5. Wellcome Trust Centre for Human Genetics , University of Oxford , Oxford , UK

6. Nuffield Department of Medicine , University of Oxford , Oxford , UK

Abstract

Abstract Future spacecraft and crew habitats are anticipated to use a moderately hypobaric and hypoxic cabin atmosphere to reduce the risk of decompression sickness associated with extravehicular activity. This has raised concerns about potential hypoxia-mediated adverse effects on astronauts. Noninvasive technology for measuring tissue oxygen saturation (StO2) has been developed for clinical use and may be helpful in monitoring oxygenation during spaceflight. We conducted a technical evaluation of a handheld StO2 monitor during a series of parabolic flights, and then undertook a preliminary analysis of the data obtained during the flights from six individuals. The StO2 monitor operated normally in all gravity conditions. There was considerable variability in StO2 between and within individuals. Overall, transition to microgravity was associated with a small decrease in StO2 of 1.1±0.3%. This evaluation has established the basic function of this technology in microgravity and demonstrates the potential for exploring its use in space.

Publisher

Walter de Gruyter GmbH

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Cardiopulmonary responses to centrifuge simulated parabolic flight;Indian Journal of Aerospace Medicine;2021-11-08

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