Study of the Properties and Cells Growth on Antibacterial Electrospun Polycaprolactone/Cefuroxime Scaffolds-Reference-Cited by-同舟云学术

Study of the Properties and Cells Growth on Antibacterial Electrospun Polycaprolactone/Cefuroxime Scaffolds

Published:2020-09-01 Issue:3 Volume:20 Page:312-318
ISSN:2300-0929
Container-title:Autex Research Journal
language:en
Short-container-title:

Author:

Mijovic Budimir¹,Zdraveva Emilija¹,Bajsić Emi Govorčin²,Slivac Igor³,Dekaris Iva⁴,Grgurić Tamara Holjevac⁵,Ferri Tea Zubin⁶

Affiliation:

1. University of Zagreb Faculty of Textile Technology, Department of Fundamental Natural and Engineering Sciences , Prilaz baruna Filipovića 28a , Zagreb , Croatia

2. University of Zagreb Faculty of Chemical Engineering and Technology, Department of Polymer Engineering and Organic Chemical Technology , Marulićev Trg 19 , Zagreb , Croatia

3. University of Zagreb Faculty of Food Technology and Biotechnology, Department of Biochemical Engineering , Pierottijeva ul. 6 , Zagreb , Croatia

4. Specialty Eye Hospital Svjetlost , Heinzelova ul. 39 , Zagreb and Department of Ophthalmology Medical Faculty , University of Rijeka , Braće Branchetta 20/1 , Rijeka , Croatia

5. University of Zagreb , Faculty of Metallurgy, Department of Physical Metallurgy , Aleja narodnih heroja 3, Sisak , , Croatia

6. Materials’ Research Center METRIS , Zagrebačka 30 , Pula , Croatia

Abstract

Abstract Electrospun materials are good candidates for the design of tissue regeneration scaffolds as they can simulate the natural surroundings of tissue cells. The study proposes electrospun polycaprolactone (PCL)/cefuroxime (CFU) scaffolds for human cell culture and investigates the influence of the antibiotic content on scaffold morphology, thermal and mechanical properties. The increase in the CFU concentration resulted in the reduction of fiber diameter and number of deformations. It also influenced the reduction of scaffold thermal enthalpies and improved scaffold break strength. With regard to cell growth, the scaffolds showed precedence in greater colonization of the HeLa cells. Finally, these scaffolds showed compatibility with standard human cell lines, and thus they can be used for the repair of damaged tissues.

Publisher

Walter de Gruyter GmbH

Subject

General Materials Science

Link

https://www.sciendo.com/pdf/10.2478/aut-2019-0036

Reference20 articles.

1. Zdraveva, E., Fang, J., Mijovic, B., Lin, T. (2016). Structure and properties of high-performance fibers; (Bhat, G., ed.) Woodhead Publishing in Association with the Textile Institute, by Elsevier: Cambridge.

2. Mijović, B., Tominac Trcin, M., Agić, A., Zdraveva, E., Bujić, M., et al. (2012). Study on Cell Adhesion Detection onto Biodegradable Electrospun PCL Scaffolds. Journal of Fiber Bioengineering & Informatics, 5(1), 33–40.

3. Zdraveva, E., Magovac, E., Mijovic, B. (2016). Elektroispredanje – značajna tehnika 21. stoljeća. Tekstil: časopis za tekstilnu tehnologiju i konfekciju, 65(11–12), 397–409.

4. Tominac Trcin, M., Dekaris, I., Mijović, B., Bujić, M., Zdraveva, E., et al. (2015). Synthetic vs natural scaffolds for human limbal stem cell cultivation. Croatian medical journal, 56(3), 246–256.

5. Stevens, M. M., George, J. H. (2005). Exploring and engineering the cell surface interface, Science, 310(5751), 1135–1138.

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. One‐dimensional nanomaterials for nerve tissue engineering to repair spinal cord injury;BMEMat;2024-08-02

2. Characterization of Electrospun Nanofibers;Nanostructure Science and Technology;2023

3. Poly(ε-caprolactone) Titanium Dioxide and Cefuroxime Antimicrobial Scaffolds for Cultivation of Human Limbal Stem Cells;Polymers;2020-08-06