Design and fabrication of 125I seeds for brachytherapy using capillary-based microfluidic technique

Author:

Wang Yuan1,Zhang Miao1,Song Tong1,Chang Zhenqi1

Affiliation:

1. University of Science and Technology of China , Department of Engineering and Applied Physics , Huang-Shan Road 443 , He-Fei , P. R. China

Abstract

Abstract A new kind of 125I seeds with a core-shell structure were synthesized by an easy assembling–disassembling coaxial capillaries microfluidic device. The dose distribution of a 125I brachytherapy source fabricated by arranging six 125I seeds collinearly within a cylindrical titanium capsule was simulated by modelling the source in a water phantom using Monte Carlo N-Particle Transport code. The influence of the motion and the core size of the 125I seeds on the dose distribution was also studied in this work.

Publisher

Walter de Gruyter GmbH

Subject

Waste Management and Disposal,Condensed Matter Physics,Safety, Risk, Reliability and Quality,Instrumentation,Nuclear Energy and Engineering,Nuclear and High Energy Physics

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