Time-Dependent Testicular and Epididymal Damage in Rabbit Bucks Experimentally Infected with Trypanosoma Brucei Brucei-Reference-Cited by-同舟云学术

Time-Dependent Testicular and Epididymal Damage in Rabbit Bucks Experimentally Infected with Trypanosoma Brucei Brucei

Published:2021-10-01 Issue:2 Volume:44 Page:139-147
ISSN:1857-7415
Container-title:Macedonian Veterinary Review
language:en
Short-container-title:

Author:

Adeyeye Adewale Ayodeji¹,Alayande Musbaudeen Olayinka²,Adio Monsurat Bansima²,Haliru Lauratu Lawal²,Abdulrafiu Aliyu²

Affiliation:

1. Department of Theriogenology and Animal Production, Faculty of Veterinary Medicine , Usmanu Danfodiyo University , Sokoto , Nigeria

2. Department of Veterinary Parasitology and Entomology, Faculty of Veterinary Medicine , Usmanu Danfodiyo University Sokoto , Sokoto

Abstract

Abstract This study was designed to determine the progressive pathological changes in the testis and epididymis of rabbit bucks experimentally infected with Trypanosoma brucei brucei (T. brucei). Fifteen local rabbit bucks were divided into 2 groups comprising 8 bucks in group A and 7 bucks in group B. Bucks in group A were infected intraperitoneally with approximately 1.0×106 of T. brucei while bucks in group B served as the uninfected control. The bucks were closely monitored for clinical signs of trypanosomosis from the time of infection till the end of the study. One buck from each group was humanely sacrificed on days 9, 19, 29 and 38 post-infection (pi) and its testis and epididymis were examined for pathological changes. At post mortem, no gross lesions were observed in the infected bucks except for adhesion of the testis and epididymis to the scrotum on days 29 and 38 pi. There were no histological changes in the testis and epididymis of the infected buck sacrificed on day 9 pi apart from mild depletion of the epididymal sperm reserve. The buck infected on day 19 pi had moderate testicular degeneration but the epididymis was devoid of sperm reserve. Severe testicular and epididymal degeneration was observed in the buck on days 29 and 38 pi. The testis and epididymis of bucks from the control group were normal with evidence of spermatogenic activities and full epididymal sperm reserve throughout. The study shows that infected bucks were unfit for breeding from day 19 pi.

Publisher

Walter de Gruyter GmbH

Subject

General Veterinary

Link

https://www.sciendo.com/pdf/10.2478/macvetrev-2021-0018

Reference42 articles.

1. 1. Swallow, B.M. (2000). Impacts of trypanosomiasis on African agriculture. [Inter net]. Food and agriculture organization of the United Nations. Rome. http://www.fao.org/3/X4755EN/x4755en.pdf

2. 2. Abubakar, Y.U., Oyedipe, E.O., Eduvie, L.O., Ogwu, D.O., Adeyeye, A.A. (2015). Reproduction and Trypanosoma congolense in Nigerian West African dwarf ewes: I. Effects on the estrous cycle. J Protozool Res. 25(1-2): 1-7.

3. 3. Adeyeye, A.A., Ate, I.U., Lawal, A.I., Adamu, S. (2016). Effects of experimental Trypanosoma evansi infection on pregnancy in Yankasa ewes. Theriogenology 85(5): 862-869. https://doi.org/10.1016/j.theriogenology.2015.10.034 PMid:2664360510.1016/j.theriogenology.2015.10.034

4. 4. Adeyeye, A.A., Ate, I.U., Lawal, A.I., Adamu, S. (2016). Postpartum pathology in Yankasa ewes experimentally infected with Trypanosoma evansi during pregnancy. Comp Clin Pathol. 25(3): 593-598. https://doi.org/10.1007/s00580-016-2236-y10.1007/s00580-016-2236-y

5. 5. Alayande, M.O., Adeyeye, A.A., Abdulrafiu, A, Adio, M.B, Halilu, L.L. (2019). Sexual dimorphism of rabbit bucks and does experimentally infected with Trypanosoma brucei brucei. Veterinaria 68(2): 81-85.