Variation of Serum Vitamin B12 Level in the Blood from Patients of Different Age Among the Latvian Population

Author:

Gavars Didzis12,Perminov Dmitry13,Tauckels Eriks1,Lindenberga Ilze1,Miķelsone Agnese2,Auce Agris4

Affiliation:

1. E. Gulbis Laboratory , 366 Brīvības Av., Rīga, LV-1006 , Latvia

2. Faculty of Medicine , Rīga Stradiņš University , 16 Dzirciema Str., Rīga, LV-1007 , Latvia

3. Faculty of Biology , University of Latvia , 19 Raiņa Blvd., Rīga, LV-1586 , Latvia

4. Institute of Chemical Physics , University of Latvia , 19 Raiņa Blvd., Rīga, LV-1586 , Latvia

Abstract

Abstract The reference intervals and median values of serum vitamin B12 level in blood from patients among the Latvian population were established for different age groups with a two-year step using data for a large number of patients, accumulated in E. Gulbis Laboratory in Latvia. The data represents the general population of Latvia. An indirect in silico method, developed in E. Gulbis laboratory for determination of serum vitamin B12 blood level reference intervals, was used. Strong elevation of serum vitamin B12 blood level was observed in children who were between 2 and 10 years old. The paper discusses the serum vitamin B12 values for children and a different serum vitamin B12 reference interval for young children is suggested.

Publisher

Walter de Gruyter GmbH

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