Schiff Bases and Triazolothiadiazines Derived from A Thiophene-Substituted 4-Amino-3-Mercapto-1,2,4-Triazole-Reference-Cited by-同舟云学术

Schiff Bases and Triazolothiadiazines Derived from A Thiophene-Substituted 4-Amino-3-Mercapto-1,2,4-Triazole

Published:2019-12-01 Issue:2 Volume:27 Page:137-154
ISSN:2067-2446
Container-title:Acta Chemica Iasi
language:en
Short-container-title:

Author:

Roman Gheorghe¹

Affiliation:

1. Department of Inorganic Polymers, Petru Poni Institute of Macromolecular Chemistry , 41A Aleea Gr. Ghica Vodă, Iaşi 700487 , Romania

Abstract

Abstract 4-Amino-5-(thiophen-2-ylmethyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione was synthesized and converted into the corresponding Schiff bases using several aromatic aldehydes. Reaction of this aminotriazolethione with phenacyl bromides lead to triazolothiadiazines, which were subsequently reduced with NaBH4 to dihydrotriazolothiadiazines. The latter type of fused heterocycle has been also obtained directly by reacting one of the previously obtained Schiff base with phenacyl bromides. NMR analysis confirmed the structures of the synthesized compounds.

Publisher

Editura Universitatii Alexandru Ioan Cuza din Iasi

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