Impact of Thiocyanate on the Catecholase Activity of Cu(II) and Fe(III) Complexes of 2-((4-(2-Hydroxy-4-Methylbenzyl)Piperazin-1-YL)Methyl)-5-Methylphenol (A Mannich Base)-Reference-Cited by-同舟云学术

Impact of Thiocyanate on the Catecholase Activity of Cu(II) and Fe(III) Complexes of 2-((4-(2-Hydroxy-4-Methylbenzyl)Piperazin-1-YL)Methyl)-5-Methylphenol (A Mannich Base)

Published:2018-07-01 Issue:1 Volume:26 Page:59-73
ISSN:2067-2446
Container-title:Acta Chemica Iasi
language:en
Short-container-title:

Author:

Ayeni Ayowole O.¹²,Watkins Gareth M.¹

Affiliation:

1. Department of Chemistry , Rhodes University , South Africa

2. Department of Chemistry , Obafemi Awolowo University , Nigeria

Abstract

Abstract Four metal complexes viz Cu(II) and Fe(III) with or without thiocyanate have been synthesized from a Mannich base prepared by a simple synthetic route. These complexes were characterized by elemental and spectroscopic techniques. Bonding modes of the thiocyanate group with the metal complexes as studied by infrared spectroscopy revealed the presence of bridging N- and S- bonding modes. Detailed kinetic studies of these complexes were carried in the evaluation of their catecholase activity. The Fe(III) complex demonstrated the highest catalytic activity using 3,5-di-tert-butyl catechol (3,5-DTBC) as substrate with a turnover rate (kcat) of 112.32 h−1.

Publisher

Editura Universitatii Alexandru Ioan Cuza din Iasi

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