Squamous Cell Carcinoma of the Skin: Epidemiology, Diagnosis, Management, Recurrence and Mortality Rates for the Bulgarian Population-Reference-Cited by-同舟云学术

Squamous Cell Carcinoma of the Skin: Epidemiology, Diagnosis, Management, Recurrence and Mortality Rates for the Bulgarian Population

Published:2023-11-01 Issue:2 Volume:16 Page:180-185
ISSN:1313-9053
Container-title:Journal of Biomedical and Clinical Research
language:en
Short-container-title:

Author:

Vasilev Preslav P.¹,Karaivanov Milen P.²,Karamanliev Martin P.³,Dimitrov Dobromir D.³,Troyanova Petranka P.⁴,Yordanova Ivelina A.¹

Affiliation:

1. 1 Department of Dermatology, Venereology and Allergology, Dr Georgi Stranski University Hospital, Faculty of Medicine , Medical University – Pleven , Bulgaria

2. 2 Department of General and Clinical Pathology, Faculty of Medicine , Medical University – Pleven , Bulgaria

3. 3 Surgical Oncology Department, Dr Georgi Stranski University Hospital, Faculty of Medicine , Medical University – Pleven , Bulgaria

4. 4 Department of Nuclear Medicine, Radiation Therapy and Medical Oncology, Tsaritsa Yoanna University Hospital, Faculty of Medicine , Medical University – Sofia , Bulgaria

Abstract

Summary Squamous cell carcinoma of the skin (SCCs) accounts for 20-30% of non-melanoma skin cancers, resulting in 1 million cases in the United States annually. The risk of developing SCCs increases annually, and this process will likely be continued because of the aging population. We investigated 355 patients with histopathologically confirmed SCCs. We rated the age- and sex-related incidence, risk factors, localisation, pathological features, staging systems and treatment, and the recurrence and mortality rates of the tumours. Staging and risk stratification for recurrence and metastases is significant. Most SCCs are successfully treated surgically, with a small subset of carcinomas leading to recurrence, metastasis, and death. Patients with advanced and metastatic disease are often inappropriate for surgical and radiation therapy. We present the first study on squamous cell carcinoma of the skin conducted for the population of the Pleven and Lovech regions of Bulgaria.

Publisher

Walter de Gruyter GmbH

Subject

General Medicine

Link

https://www.sciendo.com/pdf/10.2478/jbcr-2023-0024

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