Segmental volume and circulatory changes that occur in humans and Rhesus monkeys during 4 hour, −6 degree head down tilt

Author:

Montgomery Leslie David1,Oloff Clarence2

Affiliation:

1. LDM Associates , San Jose , USA

2. San Jose USA

Abstract

Abstract Nonhuman primates are often used to investigate physiologic processes that occur in man during aerospace/cardiovascular orthostatic research. Few studies have compared nonhuman primates and man under identical test conditions to assess the degree of similarity between the two species. Impedance plethysmography was used to measure calf, thigh, pelvic, thoracic, upper arm, and lower arm volume changes in eight rhesus (Macacca Mulatta) monkeys and twelve human subjects during four hour exposures to −6 degree head down tilt (HDT).

Publisher

Walter de Gruyter GmbH

Subject

Biomedical Engineering,Biophysics

Reference11 articles.

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2. U.S. Congress, Office of Technology Assessment, Alternatives to Animal Use in Research Testing, and Education (Washington, DC: U.S. Government Printing Office, OTA-BA-273), February 1986.

3. Montgomery LD, Parmet AJ, and Booher CR. Body volume changes duringsimulated microgravity: Auditory changes, segmental fluid redistribution, and regional hemodynamics. Annals of Biomedical Engineering. 1993: 417–433. https://doi.org/10.1007/BF02368634

4. Oloff CM. Timed primate roto-positioning method for preventing trauma and for simulating weightlessness. U.S. Patent Number 5,275,132. Jan. 4, 1994.

5. Nyboer J. Electrical impedance plethysmography. Springfield, IL. Charles C. Thomas, 1970.

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