Author:
Abd El-Latif Nehad,Abdulla Mohamed,Amr Abd
Abstract
New steroidal derivatives synthesized using 3β-hydroxyandrosten-17-one as starting materialIn this study, we synthesized some new substituted steroidal derivatives using 3β-hydroxyandrosten-17-one (dehydroepiandrosterone) as starting material. The synthesized steroidal derivatives1-11were evaluated for their androgenic-anabolic activities compared to testosterone as positive control. Details of the synthesis, spectroscopic data and toxicity (LD50) of synthesized compounds are reported.
Subject
Pharmaceutical Science,Pharmacology,General Medicine
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