Synthesis of new derivatives of 9-(2-pyridyl)-3-aryl(arylalkyl)- -2,4,5(9H)trioxo-7,8-dihydroimidazo[1,2-a][1,3,5]triazepine

Author:

Rzadkowska Marzena1,Szacon Elzbieta1,Zun Maria2

Affiliation:

1. Chair and Department of Synthesis and Chemical Technology of Pharmaceutical Substances with Computer Modeling Unit, Faculty of Pharmacy with Division of Medical Analytics, Medical University of Lublin, Chodzki 4a, 20-093 Lublin, Poland

2. Chair and Department of Applied Pharmacy, Faculty of Pharmacy, Medical University of Lublin, Chodzki 1, 20-093 Lublin, Poland

Abstract

Abstract A series of new derivatives of 9-(2-pyridyl)-3-aryl(arylalkyl)-2,4,5(9H)trioxo-7,8- dihydroimidazo [1,2-a][1,3,5] triazepine was obtained by condensation of 1-[1-(2-pyridyl) imidazolidine-2-ylidene]-3-aryl(arylalkyl)ureas) with diethyl oxalic acid ester. Considering the structure of the obtained compounds, it can be expected that these compounds can reveal pharmacological activity.

Publisher

Walter de Gruyter GmbH

Subject

Pharmacology,Molecular Biology,General Medicine,Biochemistry

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