The evaluation of lipid peroxidation and oxidative modification of proteins in blood serum under obesity development and the consumption of aqueous kidney beans Phaseolus vulgaris pods extract

Author:

Yurchenko Alona1ORCID,Krenytska Daryna1ORCID,Savchuk Olexii1ORCID,Halenova Tetiana1ORCID,Raksha Natalia1ORCID,Vovk Tetiana1ORCID,Ostapchenko Ludmyla1ORCID

Affiliation:

1. Educational and Scientific Center “Institute of Biology and Medicine” , Taras Shevchenko National University of Kyiv , Ukraine

Abstract

Abstract Our interest has focused on the investigation of the anti-obese potential of kidney beans (P. vulgaris) pods extract. In the course of the study, obesity development in rats was induced with high-calorie diet. Control and obese rats then have consumed with aqueous kidney beans (P. vulgaris) pods extract during 6 weeks (200 mg/kg). Results show that the long-term consumption of P. vulgaris pods extract can lead to the reduction of hyperglycemia and insulin resistance development. Furthermore, we saw a normalization of lipid peroxidation parameters and oxidative modification of protein due to the consumption of the kidney beans (P. vulgaris) pods extract. Our experimental data demonstrate the ability of the kidney beans (P. vulgaris) pod extracts to mitigate obesity development but the details of this mechanism remains to be not fully understood.

Publisher

Walter de Gruyter GmbH

Subject

Pharmacology,Molecular Biology,General Medicine,Biochemistry

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