Association of SNPs in AKIRIN2, TTN, EDG1 and MYBPC1 Genes with Growth and Carcass Traits in Qinchuan Cattle-Reference-Cited by-同舟云学术

Association of SNPs in AKIRIN2, TTN, EDG1 and MYBPC1 Genes with Growth and Carcass Traits in Qinchuan Cattle

Published:2022-01-01 Issue:1 Volume:22 Page:121-139
ISSN:2300-8733
Container-title:Annals of Animal Science
language:en
Short-container-title:

Author:

Cheng Zixuan¹,Sheng Cong²,Li Yaxing¹,Wang Shenyuan³,Wu Kaifeng³,Liu Jianfeng⁴,Sasaki Seiki⁵,Yamada Takahisa⁶,Ya Su⁷,Zhou Huanmin³,Zan Linsen²,Tong Bin¹

Affiliation:

1. The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock , School of Life Sciences, Inner Mongolia University , Hohhot , China

2. College of Animal Science and Technology, National Beef Cattle Improvement Center , Northwest A & F University , Yangling , China

3. Inner Mongolia Key Laboratory of Biomanufacture, College of Life Sciences , Inner Mongolia Agriculture University , Hohhot , China

4. Key Laboratory of Animal Genetics, Breeding, and Reproduction, Ministry of Agriculture, National Engineering Laboratory for Animal Breeding , College of Animal Science and Technology, China Agricultural University , Beijing , China

5. Maebashi Institute of Animal Science, Livestock Improvement Association of Japan , Maebashi , Japan

6. Department of Agrobiology, Faculty of Agriculture , Niigata University , Niigata , Japan

7. Inner Mongolia Animal Husbandry Station , Hohhot , China

Abstract

Abstract Growth and carcass traits are the main breeding objectives in beef cattle. The aim of this study was to confirm genetic effects of the c.*188G>A SNP of AKIRIN2, the g.231054C>T SNP of TTN, the g.1471620G>T SNP of EDG1 and the g.70014208A>G SNP of MYBPC1 on growth and carcass traits in Chinese Qinchuan (QC) cattle, as well as to compare the frequencies of the well-characterized alleles of these SNPs among six Chinese cattle populations, three Japanese cattle populations, two European cattle populations and one Korean cattle population. In this study, a total of 665 cattle samples were genotyped using MassARRAY and PCR-RFLP. Association analysis explored effects of four SNPs on growth and carcass traits including body length, wither height, hip height, hip width, rump length, chest depth, chest circumference, back fat thickness, ultrasound longissimus muscle area and ultrasound longissimus muscle depth in QC (P<0.05 to P<0.001). The well-characterized A (c.*188G>A), T (g.231054C>T) and T (g.1471620G>T) alleles in Japanese Black cattle were significantly higher than Chinese cattle breeds; on the contrary, the G allele (g.70014208A>G) was markedly higher in Chinese cattle breeds than other cattle breeds. These results suggest that the four SNPs might be useful as a molecular marker for growth-related traits in Chinese QC cattle.

Publisher

Walter de Gruyter GmbH

Link

https://www.sciendo.com/pdf/10.2478/aoas-2021-0025

Reference50 articles.

1. Andersson L. (2001). Genetic dissection of phenotypic diversity in farm animals. Nat. Rev. Genet., 2: 130–138.

2. Andersson L., Georges M. (2004). Domestic-animal genomics: Deciphering the genetics of complex traits. Nat. Rev. Genet., 5: 202–212.

3. Boichard D., Grohs C., Bourgeois F., Cerqueira F., Faugeras R., Neau A., Rupp R., Amigues Y., Boscher M.Y., Levéziel H. (2003). Detection of genes influencing economic traits in three French dairy cattle breeds. Genet. Sel. Evol., 35: 77–101.

4. Casas E., Stone R.T., Keele J.W., Shackelford S.D., Kappes S.M., Koohmaraie M. (2001). A comprehensive search for quantitative trait loci affecting growth and carcass composition of cattle segregating alternative forms of the myostatin gene. J. Anim. Sci., 79: 854–860.

5. Casas E., Shackelford S.D., Keele J.W., Koohmaraie M., Smith T.P.L., Stone R.T. (2003). Detection of quantitative trait loci for growth and carcass composition in cattle. J. Anim. Sci., 81: 2976–2983.