Affiliation:
1. Tîrgu Mureş County Emergency Clinical Hospital ,
2. “George Emil Palade” University of Medicine, Pharmacy, Science and Technology , Tîrgu Mureş
Abstract
Abstract
Hepatocellular carcinoma is one of the most common liver tumours. At the time of diagnosis, only 20% of patients are suitable for liver resection for curative purposes. In patients who are not suitable for surgical resection, chemoembolization of the hepatic artery is a viable therapeutic option. We present the case of a 60-year-old male patient being admitted with a diagnosis of liver tumour in the right liver lobe. Abdominal angio-CT examination revealed the existence of a tumour formation of 9x10 cm in the liver segments IV, VIII. Given the large size of the tumour, as well as the patient’s comorbidities, it was decided to practice hepatic chemoembolization with Irinotecan. The clinical evolution was favourable, the patient being discharged 48 hours after the intervention. Hepatic transarterial chemoembolization is a viable alternative in the treatment of patients with unresectable hepatocellular carcinomas, which may improve the prognosis of these patients.
Reference44 articles.
1. 1. Katsanos K, Kitrou P, Spiliopoulos S, Maroulis I, Petsas T, Karnabatidis D., Comparative effectiveness of different transarterial embolization therapies alone or in combination with local ablative or adjuvant systemic treatments for unresectable hepatocellular carcinoma: A network meta-analysis of randomized controlled trialsPLoS One. 2017 Sep 21;12(9):e0184597. doi: 10.1371/journal.pone.0184597
2. 2. Bruix J, Sherman M, Practice Guidelines Committee AAftSoLD. Management of hepatocellular carcinoma. Hepatology. 2005;42(5):1208-36. pmid:16250051.
3. 3. Bruix J, Reig M, Sherman M. Evidence-Based Diagnosis, Staging, and Treatment of Patients with Hepatocellular Carcinoma. Gastroenterology. 2016;150(4):835-53. pmid:26795574.
4. 4. Ray CE Jr., Brown AC, Green TJ, Winston H, Curran C, Kreidler SM, et al. Survival outcomes in patients with advanced hepatocellular carcinoma treated with drug-eluting bead chemoembolization. AJR American journal of roentgenology. 2015;204(2):440–7. pmid:25615768.
5. 5. Fu Y, Zhao X, Yun Q, Zhu X, Zhu Y, Li Q, et al. Transarterial chemoembolization (TACE) plus percutaneous ethanol injection (PEI) for the treatment of unresectable hepatocellular carcinoma: a meta-analysis of randomized controlled trials. International journal of clinical and experimental medicine. 2015;8(7):10388-400. pmid:26379829.