Risk Factors Regarding Portal Vein Thrombosis in Chronic Liver Disease

Author:

Vecerzan Liliana1,Mihăilă Romeo Gabriel2

Affiliation:

1. PhD candidate “Lucian Blaga” University of Sibiu

2. Lucian Blaga” University of Sibiu, Emergency County Clinical Hospital , Sibiu

Abstract

Abstract The portal vein thrombosis (PVT) is one of the most frequent vascular diseases of the liver, with a high rate of morbidity and mortality. The most common causes of the PVT are hepatic cirrhosis, hepatobiliary neoplasms, inflammatory and infectious abdominal diseases, and myeloproliferative syndromes.(1,2) The natural progress of the PVT has as a result portal hypertension which leads to splenomegaly and the formation of portosystemic collateral vessels, as well as gastroesophageal, duodenal and jejunal varices. Ultrasonography, especially Doppler ultrasound, is the most widely used imaging method to asses, supervise and diagnose PVT in patients with hepatopathies. The purpose of acute PVT treatment is to re-permeabilize the obstructed vessels; the endoscopic ligature of the varices in the eventuality of their rupture is safe and extremely efficient in chronic PVT. To conclude, PVT is the most common hepatic vascular disorder, and its prevalence has increased particularly among the patients with chronic hepatopathies.(3)

Publisher

Walter de Gruyter GmbH

Reference15 articles.

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2. 2. Gîrleanu I, Trifan A, Stanciu C, et al. Portal vein thrombosis in cirrhotic patients - it is always the small pieces that make the big picture, World J Gastroenterol, October 2018;24(39):4419-4427, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196341/, Accessed on 06.05.2020.10.3748/wjg.v24.i39.4419

3. 3. Hoekstra J, Janssen HL. Vascular liver disorders (II): portal vein thrombosis, Neth J Med. 2009;67(2):46-53, https://pubmed.ncbi.nlm.nih.gov/19299846/, Accessed on 06.05.2020.

4. 4. Vecerzan L, Boicean A, Cipăian CR, et al. The correlation between conventional coagulation tests and the study of thrombin generation in patients with liver cirrhosis, Acta Medica Transilvanica. 2019:24(2):31-33.

5. 5. Chen H, Trilok G, Wang F, et al. A single hospital study on portal vein thrombosis in cirrhotic patients - clinical characteristics & risk factors, Indian J Med Res. 2014 Feb; 139(2):260-266.

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