Intraventricular tuberculosis abscess in an immunocompromised patient: clinical vignette

Author:

Hanafiah Mohamad1ORCID,Mukhari Shahizon A Mohamed2ORCID,Mustapha Aida M3ORCID,Mumin Nazimah Ab4ORCID

Affiliation:

1. Department of Radiology, Sunway Medical Centre , Jalan Lagoon Selatan, Bandar Sunway , Petaling Jaya , Selangor , Malaysia

2. Department of Radiology, Hospital Canselor Tuanku Muhriz , Universiti Kebangsaan Malaysia , Jalan Yaacob Latif, Bandar Tun Razak , Cheras , Kuala Lumpur , Malaysia

3. Department of Radiology, Hospital Shah Alam , Persiaran Kayangan 7 , Shah Alam , Selangor , Malaysia

4. Department of Radiology, Faculty of Medicine , University Teknologi Mara , Shah Alam , Selangor , Malaysia

Abstract

Abstract Tuberculosis is caused by Mycobacterium tuberculosis. Tuberculosis of the central nervous system is common and manifestations include meningeal and intraparenchymal diseases. However, intraventricular tuberculous abscess is a rare manifestation of intracranial tuberculous infection. We present a case of an immunocompromised female patient with high-grade fever and signs of meningism. The computed tomography and magnetic resonance imaging (MRI) of the brain showed hydrocephalus with rim-enhancing lesion in the right lateral ventricle. The MRI demonstrated a hypointense signal on T1-weighted imaging, hyperintense signal on T2-weighted imaging, and mild restricted diffusion in diffusion-weighted imaging. She underwent emergency external ventricular drainage and frank pus was drained. Diagnosis of tuberculosis was made via polymerase chain reaction analysis and culture. Understanding the intracranial manifestation of neurotuberculosis is imperative to arrive at the diagnosis correctly and ensure prompt treatment.

Publisher

Walter de Gruyter GmbH

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