Abstract
AbstractIn the adult human fronto-opercular cortex, the grade of granularity of cortical layer IV represents a major architectonic feature for distinguishing the opercular area BA44 (which is typically described as being magnopyramidal and intermedio-granular) from the triangular area BA45 (which is typically described as being magnopyramidal and granular). We analyzed postnatal cytoarchitectonic development of internal granular layer (layer IV) of the fronto-opercular region in 23 brains of newborns, infants and children (age range: 15 days to 15 years) and in one adult brain. We found that: (1) the grade of granularity of layer IV in the fronto-opercular cortex displays a great interindividual variability throughout development as well as in the adult brain; (2) this variability is much more pronounced in the opercular area BA44 than in the triangular area BA45. Our findings support the classical interpretation provided by Constantin von Economo (von Economo & Koskinas, 1925) according to which BA44/FCBm represents a specialized variant of the wide premotor cortical zone, while BA45/FDG represents a specialized variant of the typical (associative) frontal granular cortex.
Reference37 articles.
1. Brodmann K., Beiträge zur histologischen Lokalisation der Grosshirnrinde. VI. Mitteilung: Die Cortexgliederung des Menschen. J. Psychol. Neurol. (Leipzig), 1908, 10, 231–246
2. Ojemann G.A., Cortical organization of language. J. Neurosci., 1991, 11, 2281–2287
3. Bookheimer S., Functional MRI of language: New approaches to understanding the cortical organization of semantic processing. Annu. Rev. Neurosci., 2002, 25, 151–188
4. Judaš M., Cepanec M., Adult structure and development of the human fronto-opercular cerebral cortex (Broca’s region). Clin. Ling. Phonetics, 2007, 21, 975–989
5. Rizzolatti G., Arbib M.A., (1998) Language within our grasp. Trends Neurosci., 1998, 21, 188–194
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献