A Race Against Time: Coronary Computed Tomography Angiography Discovers a Highly Inflamed Plaque in 49-Year-Old Right Before STEMI-Reference-Cited by-同舟云学术

A Race Against Time: Coronary Computed Tomography Angiography Discovers a Highly Inflamed Plaque in 49-Year-Old Right Before STEMI

Published:2023-12-09 Issue:0 Volume:0 Page:
ISSN:2457-5518
Container-title:Journal of Cardiovascular Emergencies
language:en
Short-container-title:

Author:

Mátyás Botond-Barna¹²,Blîndu Emanuel¹²,Rat Nóra¹³,Kovács István¹³,Buicu Corneliu-Florin⁴,Benedek Theodora¹³

Affiliation:

1. Clinic of Cardiology , Mureș County Emergency Clinical Hospital , Târgu Mureș , Romania

2. Doctoral School of “George Emil Palade” University of Medicine, Pharmacy, Science and Technology , Târgu Mureș , Romania

3. Department of Cardiology , “George Emil Palade” University of Medicine, Pharmacy, Science and Technology , Târgu Mureș , Romania

4. Public Health and Management Department , “George Emil Palade” University of Medicine, Pharmacy, Science and Technology , Târgu Mureș , Romania

Abstract

Abstract In the modern management of coronary artery disease (CAD), cardiac computed tomography angiography (CCTA) has emerged as a pivotal diagnostic tool, offering detailed visualization of coronary artery lumens and atherosclerotic plaques. We present the case of a 49-year-old woman, with no prior cardiovascular history but with several risk factors, in whom CCTA identified a highly inflamed atherosclerotic plaque, which led immediately to an acute myocardial infarction. Significantly, this case spotlights the vital role of perivascular inflammation mapping in CCTA, crucial for identifying high-risk plaques. The case emphasizes the necessity for a comprehensive, multifaceted diagnostic approach in the evaluation and management of CAD, incorporating advanced techniques like perivascular inflammation mapping for a more accurate and predictive assessment.

Publisher

Walter de Gruyter GmbH

Subject

General Medicine

Link

https://www.sciendo.com/pdf/10.2478/jce-2023-0018

Reference19 articles.

1. Knuuti J, Wijns W, Saraste A, et al. 2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes: the Task Force for the diagnosis and management of chronic coronary syndromes of the European Society of Cardiology (ESC). European Heart Journal. 2020;41:407–477. doi: 10.1093/eurheartj/ehz425.

2. Anderson H, Masri SC, Abdallah MS, et al. 2022 ACC/AHA Key Data Elements and Definitions for Chest Pain and Acute Myocardial Infarction: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Data Standards. Circ Cardiovasc Qual Outcomes. 2022;15:e000112. doi: 10.1161/HCQ.0000000000000112.

3. Rodean IP, Lazăr L, Halațiu VB, Biriș C, Benedek I, Benedek T. Periodontal Disease Is Associated with Increased Vulnerability of Coronary Atheromatous Plaques in Patients Undergoing Coronary Computed Tomography Angiography – Results from the Atherodent Study. J Clin Med. 2021;10:1290. doi: 10.3390/jcm10061290.

4. Benedek I, Bucur O, Benedek T. Intracoronary infusion of mononuclear bone marrow-derived stem cells is associated with a lower plaque burden after four years. J Atheroscler Thromb. 2014;21:217–229. doi: 10.5551/jat.19745.

5. Motoyama S, Ito H, Sarai M, et al. Plaque characterization by coronary computed tomography angiography and the likelihood of acute coronary events in mid-term follow-up. J Am Coll Cardiol. 2015;66:337–346. doi: 10.1016/j.jacc.2015.05.069.

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