Affiliation:
1. 1 “Victor Babes” Hospital , Pulmonology Department , Timisoara , Romania
2. 2 University of Medicine and Pharmacy Dr. Victor Babes , Timisoara , Romania
3. 3 Department of Pulmonology, Center for Research and Innovation in Precision Medicine of Respiratory Diseases , “Victor Babes” University of Medicine and Pharmacy Timisoara , Eftimie Murgu Sq. No. 2, 300041 Timisoara , Romania
4. 4 Polytechnic University of Timisoara , Romania
Abstract
Abstract
Introduction
We analyse anthropometric, somnopolygraphic and comorbidities data in patients with OSA syndrome, OSA with COPD, and OSA with COPD and obesity.
Material and method
2644 OSA patients, three groups: I – OSA (2112 pts., 79.9%); II – OSA and COPD (116 pts., 4.4%); III – OSA, COPD and obesity (416 pts., 15.7%).
Results
significantly older (p < 0.01, p = 001, p < 0.01); more men: 68.4% vs. 80.2% vs. 78.8%; smokers 59.4% vs. 70.7% vs. 74.3%; larger neck circumference: 42.74 ± 5.08 cm vs. 40.57 ± 3.97 cm vs. 45.90 ± 4.92 cm; higher BMI; lower O2 saturation: p < 0.01, p= 123, P < 0.01; higher desaturation index: 30.65 ± 26.96 vs. 18.94 ± 20.28 vs. 42.28 ± 29.02; lowest O2 saturation: (p < 0.01 0, p = 024, p< 0.01); higher AHI: p= 0.001, p < 0.01, p < 0.01; coronary artery disease: p < 0.01, p = 195, p < 0.01; heart failure: p < 0.01, p = 760, p < 0.01; arrhythmias: p < 0.01, p = 796, P < 0.01; stroke: unsignificant; diabetes mellitus: p = 0.252, p = 0.007, p = 0.794; systemic hypertension: p < 0.01, p = 0.786, p < 0.01.
Conclusion
COPD in OSA is more severe, with more diabetes and longer hypertension duration, but not significantly different for O2 saturation, CAD, heart failure, arrhythmia, stroke and systemic hypertension. Obesity adds to overlap OSA–COPD significant burden for all recorded data, with the exception of stroke and diabetes.