Analysis of Cell Death by Image Processing

Author:

Ždímalová Mária1,Bohumel Tomáš1,Plachá-Gregorovská Kataŕına2,Weismann Peter3,el Faloughy Hisham3

Affiliation:

1. Slovak University of Technology in Bratislava , Slovak Republic

2. Institute of Experimental Pharmacology and Toxicology, Slovak Academy of Sciences , Bratislava , Slovak Republic

3. Institute of Anatomy , Faculty of Medicine , Comenius University , Bratislava , Slovak Republic

Abstract

Abstract In this paper, we present a graph theoretical approach to image processing with focus on the analysis of the biological data. We use the graph cut algorithms and extend them to obtain a segmentation of the biological cells. We introduce an utterly new algorithm for analysis of the resulting data and for sorting them into three main categories, which correspond to the biological cell death, based on the mathematical properties of the segmented elements.

Publisher

Walter de Gruyter GmbH

Reference27 articles.

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2. [2] BOYKOV, Y.—JOLLY, M. P.: Interactive graph cuts for optimal boundary and region segmentation of objects in N-D images, In: Proceedings of International Conference on Computer Vision, Vancouer, Canada, 2001, pp. 105–112.

3. [3] BONDY, J. A.—MURTY, U. S.: Graph Theory with Applications, Great Britain, The Macmillan Press L.t.d, 1976.10.1007/978-1-349-03521-2

4. [4] CARPENTER, A.—JONES, T.—LAMPRECHT, M. ET ALL: Cell Profiler: image analysis software for identifying and quantifying cell phenotypes, Genome Biol. 7 (2006), 1–11.10.1186/gb-2006-7-10-r100

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