1. Ryan McNeil is with the Program in Addiction Medicine, Yale University, New Haven, CT. Marie Jauffret-Roustide is with Centre d’Études des Mouvements Sociaux (Inserm U1276/CNRS UMR 8044/EHESS), Paris, France, and the Social Science, Drugs and Society Program, Paris, France. Helena Hansen is with the Research Theme in Health Equity Research and Translational Social Science, David Geffen School of Medicine, University of California, Los Angeles. The authors are also Guest Editors for this supplement issue.