Beyond humanization and de-immunization: tolerization as a method for reducing the immunogenicity of biologics
Author:
Publisher
Informa UK Limited
Subject
Pharmacology (medical),General Pharmacology, Toxicology and Pharmaceutics,General Medicine
Link
http://www.tandfonline.com/doi/pdf/10.1586/17512433.2013.835698
Reference85 articles.
1. Effect of HLA DR epitope de-immunization of Factor VIII in vitro and in vivo
2. Thrombolytic agents
3. Immune tolerance induction to enzyme-replacement therapy by co-administration of short-term, low-dose methotrexate in a murine Pompe disease model
4. Successful immune tolerance induction to enzyme replacement therapy in CRIM-negative infantile Pompe disease
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