What lessons can be learned from failed Alzheimer’s disease trials?
Author:
Publisher
Informa UK Limited
Subject
Pharmacology (medical),General Pharmacology, Toxicology and Pharmaceutics,General Medicine
Link
http://www.tandfonline.com/doi/pdf/10.1586/17512433.2015.1034690
Reference19 articles.
1. Interpreting Alzheimer’s disease clinical trials in light of the effects on amyloid-β
2. Pharmacodynamics of Selective Inhibition of γ-Secretase by Avagacestat
3. Robust Central Reduction of Amyloid- in Humans with an Orally Available, Non-Peptidic -Secretase Inhibitor
4. A γ-secretase inhibitor decreases amyloid-β production in the central nervous system
5. A Phase 3 Trial of Semagacestat for Treatment of Alzheimer's Disease
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