Abiraterone acetate, a first-in-class CYP17 inhibitor, establishes a new treatment paradigm in castration-resistant prostate cancer
Author:
Publisher
Informa UK Limited
Subject
Pharmacology (medical),Oncology
Link
http://www.tandfonline.com/doi/pdf/10.1586/era.11.196
Reference20 articles.
1. Anti-androgens and androgen-depleting therapies in prostate cancer: new agents for an established target
2. Gene Expression Analysis of Human Prostate Carcinoma during Hormonal Therapy Identifies Androgen-Responsive Genes and Mechanisms of Therapy Resistance
3. Selective Inhibition of CYP17 With Abiraterone Acetate Is Highly Active in the Treatment of Castration-Resistant Prostate Cancer
4. Biology of Progressive, Castration-Resistant Prostate Cancer: Directed Therapies Targeting the Androgen-Receptor Signaling Axis
5. Antitumour activity of MDV3100 in castration-resistant prostate cancer: a phase 1–2 study
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1. P2Y1 agonist HIC in combination with androgen receptor inhibitor abiraterone acetate impairs cell growth of prostate cancer;Apoptosis;2022-02-07
2. Abiraterone In Vitro Is Superior to Enzalutamide in Response to Ionizing Radiation;Frontiers in Oncology;2021-07-21
3. Abiraterone and D4, 3-keto Abiraterone binding to CYP17A1, a structural comparison study by molecular dynamic simulation;Steroids;2021-03
4. A steady state system for in vitro evaluation of steroidogenic pathway dynamics: Application for CYP11B1, CYP11B2 and CYP17 inhibitors;The Journal of Steroid Biochemistry and Molecular Biology;2019-04
5. Low dose versus standard dose of corticosteroids in the management of adverse events of special interest from abiraterone acetate: data from a literature-based meta-analysis;Medical Oncology;2017-08-29
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