高齢進行期パーキンソン病患者におけるサフィナミドのモーニングオフ改善効果
Author:
Affiliation:
1. Emeritus Professor, Tokai University
2. Department of Clinical Technology, Tokai University Hospital
3. Director of a Hospital, Atsugi Sato Hospital
4. Professor, Department of Neurology, Tokai University Oiso Hospital
Publisher
The Japan Geriatrics Society
Subject
Geriatrics and Gerontology
Link
https://www.jstage.jst.go.jp/article/geriatrics/60/4/60_60.390/_pdf
Reference22 articles.
1. 1) Poewe W, Seppi K, Tanner CM, Halliday GM, Brundin P, Volkmann J, et al.: Parkinson disease. Nat Rev Dis Primers 2017; 3: 17013.
2. 2) Onozawa R, Tsugawa J, Tsuboi Y, Fukae J, Mishima T, Fujioka S: The impact of early morning off in Parkinson's disease on patient quality of life and caregiver burden. J Neurol Sci 2016; 364: 1-5.
3. 3) Rizos A, Martinez-Martin P, Odin P, Antonini A, Kessel B, Kozul TK, et al.: Characterizing motor and non-motor aspects of early-morning off periods in Parkinson's disease: an international multicenter study. Parkinsonism Relat Disord 2014; 20: 1231-1235.
4. 4) 日本神経学会ガイドライン作成委員会: パーキンソン病診療ガイドライン2018, 医学書院, 2018, p58-61, 116-117.
5. 5) Marzo A, Dal Bo L, Monti NC, Crivelli F, Ismaili S, Caccia C, et al.: Pharmacokinetics and pharmacodynamics of safinamide, a neuroprotectant with antiparkinsonian and anticonvulsant activity. Pharmacol Res 2004; 50: 77-85.
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