Impact of Varicocele Repair on Semen Parameters in Infertile Men: A Systematic Review and Meta-Analysis

Author:

Agarwal Ashok1ORCID,Cannarella Rossella23ORCID,Saleh Ramadan4ORCID,Boitrelle Florence56ORCID,Gül Murat7ORCID,Toprak Tuncay8ORCID,Salvio Gianmaria9ORCID,Arafa Mohamed1011ORCID,Russo Giorgio I.12ORCID,Harraz Ahmed M.131415ORCID,Singh Rajender16ORCID,Garrido Nicolas17ORCID,Hamoda Taha Abo-Almagd Abdel-Meguid1819ORCID,Rambhatla Amarnath20ORCID,Kavoussi Parviz21ORCID,Kuroda Shinnosuke3ORCID,Çalik Gökhan22ORCID,Saini Pallavi16ORCID,Ceyhan Erman23ORCID,Dimitriadis Fotios24ORCID,Henkel Ralf252627ORCID,Crafa Andrea2ORCID,Palani Ayad28ORCID,Duran Mesut Berkan29ORCID,Maziotis Evangelos3031ORCID,Saïs Émine56ORCID,Bendayan Marion56ORCID,Darbandi Mahsa3233ORCID,Le Tan V.3435ORCID,Gunes Sezgin36ORCID,Tsioulou Petroula30ORCID,Sengupta Pallav37ORCID,Hazir Berk38ORCID,Çeker Gökhan3940ORCID,Darbandi Sara3233ORCID,Durairajanayagam Damayanthi41ORCID,Aghamajidi Azin42ORCID,Alkhalidi Noora43ORCID,Sogutdelen Emrullah44ORCID,Leisegang Kristian45ORCID,Alarbid Abdullah14ORCID,Ho Christopher C. K.46ORCID,Malhotra Vineet47ORCID,Finocchi Federica948ORCID,Crisóstomo Luís495051ORCID,Kosgi Raghavender52ORCID,ElBardisi Haitham1011ORCID,Zini Armand53ORCID,Birowo Ponco54ORCID,Colpi Giovanni55ORCID,Park Hyun Jun5657ORCID,Serefoglu Ege Can58ORCID,Nguyen Quang5960ORCID,Ko Edmund61ORCID,de la Rosette Jean62ORCID,Pinggera Germar M.63ORCID,Nguyen Ho Vinh Phuoc3435ORCID,Kandil Hussein64ORCID,Shah Rupin65ORCID

Affiliation:

1. Global Andrology Forum, American Center for Reproductive Medicine, Moreland Hills, OH, USA.

2. Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.

3. Glickman Urological & Kidney Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.

4. Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Sohag University, Sohag, Egypt.

5. Department of Reproductive Biology, Fertility Preservation, Andrology, CECOS, Poissy Hospital, Poissy, France.

6. Department of Biology, Reproduction, Epigenetics, Environment and Development, Paris Saclay University, UVSQ, INRAE, BREED, Jouy-en-Josas, France.

7. Department of Urology, Selcuk University School of Medicine, Konya, Türkiye.

8. Department of Urology, Fatih Sultan Mehmet Training and Research Hospital, University of Health Sciences, Istanbul, Türkiye.

9. Department of Endocrinology, Polytechnic University of Marche, Ancona, Italy.

10. Department of Urology, Hamad Medical Corporation, Doha, Qatar.

11. Department of Urology, Weill Cornell Medical-Qatar, Doha, Qatar.

12. Urology Section, University of Catania, Catania, Italy.

13. Mansoura University Urology and Nephrology Center, Mansoura, Egypt.

14. Department of Surgery, Urology Unit, Farwaniya Hospital, Farwaniya, Kuwait.

15. Department of Urology, Sabah Al Ahmad Urology Center, Kuwait City, Kuwait.

16. Division of Endocrinology, Central Drug Research Institute, Lucknow, India.

17. IVI Foundation, Instituto de Investigación Sanitaria La Fe (IIS La Fe), Valencia, Spain.

18. Department of Urology, King Abdulaziz University, Jeddah, Saudi Arabia.

19. Department of Urology, Faculty of Medicine, Minia University, Minia, Egypt.

20. Department of Urology, Vattikuti Urology Institute, Henry Ford Health System, Detroit, MI, USA.

21. Austin Fertility & Reproductive Medicine/Westlake IVF, Austin, TX, USA.

22. Department of Urology, Faculty of Medicine, Istanbul Medipol University, Istanbul, Türkiye.

23. Department of Urology, Baskent University Faculty of Medicine, Ankara, Türkiye.

24. Department of Urology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.

25. Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.

26. Department of Medical Bioscience, University of the Western Cape, Bellville, South Africa.

27. LogixX Pharma, Theale, Berkshire, UK.

28. Research Centre, University of Garmian, Kalar, Iraq.

29. Department of Urology, School of Medicine, Pamukkale University, Denizli, Türkiye.

30. Laboratory of Physiology, Medical School, National and Kapodistrian University of Athens, Athens, Greece.

31. Assisted Reproduction Unit, Second Department of Obstetrics and Gynecology, Aretaieion Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.

32. Fetal Health Research Center, Hope Generation Foundation, Tehran, Iran.

33. Gene Therapy and Regenerative Medicine Research Center, Hope Generation Foundation, Tehran, Iran.

34. Department of Andrology, Binh Dan Hospital, Ho Chi Minh City, Vietnam.

35. Department of Urology and Andrology, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam.

36. Department of Medical Biology, Faculty of Medicine, Ondokuz Mayis University, Samsun, Türkiye.

37. Department of Biomedical Sciences, College of Medicine, Gulf Medical University, Ajman, UAE.

38. Reproductive Medicine, Department of Translational Medicine, Lund University, Malmö, Sweden.

39. Department of Urology, Başakşehir Çam and Sakura City Hospital, Istanbul, Türkiye.

40. Department of Embryology and Histology, Zonguldak Bülent Ecevit University Institute of Health Sciences, Zonguldak, Türkiye.

41. Department of Physiology, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh Campus, Selangor, Malaysia.

42. Department of Immunology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

43. Department of Internal Medicine, Trinity Health/Mercy Health, Muskegon, MI, USA.

44. Department of Urology, Bolu Abant Izzet Baysal University, Bolu, Türkiye.

45. School of Natural Medicine, Faculty of Community and Health Sciences, University of the Western Cape, Bellville, South Africa.

46. Department of Surgery, School of Medicine, Faculty of Health and Medical Sciences, Taylor’s University, Subang Jaya, Malaysia.

47. Department of Urology and Andrology, VNA Hospital, New Delhi, India.

48. Unit of Andrology and Reproductive Medicine, Department of Medicine, University of Padua, Padua, Italy.

49. Unidade Multidisciplinar de Investigação Biomédica (UMIB), Instituto de Ciências Biomédicas Abel Salazar (ICBAS), Universidade do Porto, Porto, Portugal.

50. Laboratory for Integrative and Translational Research in Population Health (ITR), Universidade do Porto, Porto, Portugal.

51. Institute of Biomedicine, University of Turku, Turku, Finland.

52. Department of Urology and Andrology, AIG Hospitals, Gachibowli, Hyderabad, India.

53. Department of Surgery, McGill University, Montreal, QC, Canada.

54. Department of Urology, Cipto Mangunkusumo General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.

55. Andrology and IVF Center, Next Fertility Procrea, Lugano, Switzerland.

56. Department of Urology, Pusan National University School of Medicine, Busan, Korea.

57. Medical Research Institute of Pusan National University Hospital, Busan, Korea.

58. Department of Urology, Biruni University School of Medicine, Istanbul, Türkiye.

59. Center for Andrology and Sexual Medicine, Viet Duc University Hospital, Hanoi, Vietnam.

60. Department of Urology, Andrology and Sexual Medicine, University of Medicine and Pharmacy, Vietnam National University, Hanoi, Vietnam.

61. Department of Urology, Loma Linda University Health, Loma Linda, CA, USA.

62. Department of Urology, Faculty of Medicine, Istanbul Medipol Mega University Hospital, Istanbul, Türkiye.

63. Department of Urology, Innsbruck Medical University, Innsbruck, Austria.

64. Fakih IVF Fertility Center, Abu Dhabi, UAE.

65. Division of Andrology, Department of Urology, Lilavati Hospital and Research Centre, Mumbai, India.

Publisher

XMLink

Subject

Pharmacology (medical),Urology,Psychiatry and Mental health,Public Health, Environmental and Occupational Health,Health Policy,Aging,Reproductive Medicine

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