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Transcription Factor Nrf2 and Mitochondria – Friends or Foes in the Regulation of Aging Rate

  • Published:2022-12 Issue:12-13 Volume:87 Page:1477-1486
  • ISSN:0006-2979
  • Container-title:Biochemistry (Moscow)
  • language:en
  • Short-container-title:Biochemistry Moscow

Author:

Shilovsky Gregory A.,Ashapkin Vasily V.

Publisher

Pleiades Publishing Ltd

Subject

Biochemistry,General Medicine,Biochemistry, Genetics and Molecular Biology (miscellaneous),Biophysics,Geriatrics and Gerontology

Reference105 articles.

1. Skulachev, V. P., Shilovsky, G. A., Putyatina, T. S., Popov, N. A., Markov, A. V., Skulachev, M. V., and Sadovnichii, V. A. (2020) Perspectives of Homo sapiens lifespan extension: focus on external or internal resources? Aging (Albany NY), 12, 5566-5584, https://doi.org/10.18632/aging.102981.

2. Lewis, K. N., Wason, E., Edrey, Y. H., Kristan, D. M., Nevo, E., and Buffenstein, R. (2015) Regulation of Nrf2 signaling and longevity in naturally long-lived rodents, Proc. Natl. Acad. Sci. USA, 112, 3722-3727, https://doi.org/10.1073/pnas.1417566112.

3. Skulachev, M. V., Severin, F. F., and Skulachev, V. P. (2015) Aging as an evolvability-increasing program which can be switched off by organism to mobilize additional resources for survival, Curr. Aging Sci., 8, 95-109, https://doi.org/10.2174/1874609808666150422122401.

4. Skulachev, V. P., Holtze, S., Vyssokikh, M. Y., Bakeeva, L. E., Skulachev, M. V., Markov, A. V., Hildebrandt, T. B., and Sadovnichii, V. A. (2017) Neoteny, prolongation of youth: from naked mole rats to “naked apes” (humans), Physiol. Rev., 97, 699-720, https://doi.org/10.1152/physrev.00040.2015.

5. Vyssokikh, M. Y., Holtze, S., Averina, O. A., Lyamzaev, K. G., Panteleeva, A. A., Marey, M. V., Zinovkin, R. A., Severin, F. F., Skulachev, M. V., Fasel, N., Hildebrandt, T. B., and Skulachev, V. P. (2020) Mild depolarization of the inner mitochondrial membrane is a crucial component of an anti-aging program, Proc. Natl. Acad. Sci. USA, 117, 6491-6501, https://doi.org/10.1073/pnas.1916414117.

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