Preparation of 177Lu Using Vacuum Sublimation Technology
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Published:2023-04
Issue:2
Volume:65
Page:198-204
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ISSN:1066-3622
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Container-title:Radiochemistry
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language:en
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Short-container-title:Radiochemistry
Author:
Alekseev I. E.,Krotov S. A.
Abstract
Abstract
A simple sublimation technology for the lutetium and ytterbium separation was proposed, which already at the stage of preliminary experiments showed effectiveness: (a) the completeness of Yb separation resulted in short-term thermal annealing is at least 98%, the distilled product is completely free from 177Lu, no additional preparation of ytterbium for repeated irradiation is required ; (b) traditional ion-exchange chromatography can be used for the final purification of 177Lu from ytterbium.
Publisher
Pleiades Publishing Ltd
Subject
Physical and Theoretical Chemistry
Reference46 articles.
1. Wehrmann, C., Senftleben, S., Zachert, C., Müller, D., and Baum, R.P., Cancer Biother. Radiopharm., 2017, vol. 22, pp. 406–416. 2. Kwekkeboom, D.J., de Herder, W.W., and Kam, B.L., J. Clin. Oncol., 2008, vol. 26, pp. 2124–2130. 3. Lee, S.-Y., Hong, Y.-D., Pyun, M.-S., Felipe, P.M., and Choi, S.J., Appl. Radiat. Isot., 2009, vol. 67, pp. 1185–1189. 4. Van Essen, M., Krenning, E.P., Kam, B.L., de Herder, W.W., Feelders, R.A., and Kwekkeboom, D.J., J. Nucl. Med., 2010, vol. 51, pp. 383–389. 5. Lehenberger, S., Barkhause, C., Cohrs, S., Fischer, E., Grünberg, J., Hohn, A., Köster, U., Schibli, R., Türler, A., and Zhernosekov, K., Nucl. Med. Biol., 2011, vol. 38, pp. 917–924.
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