Nanodiamonds as Lutetium-177 Carriers for Nuclear Medicine
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Published:2024-04
Issue:2
Volume:66
Page:191-197
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ISSN:1066-3622
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Container-title:Radiochemistry
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language:en
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Short-container-title:Radiochemistry
Author:
Kazakov A. G.,Babenya J. S.,Ekatova T. Y.,Vinokurov S. E.,Khvorostinin E. Y.,Ushakov I. A.,Zukau V. V.,Stasyuk E. S.,Nesterov E. A.,Sadkin V. L.,Rogov A. S.,Myasoedov B. F.
Abstract
Abstract
The work investigated the sorption of no-carrier-added 177Lu isolated from neutron-irradiated 176Yb2O3, and carrier-added 177Lu obtained by irradiation of natLu2O3, by commercial and oxidized nanodiamonds (NDs) of various grades from aqueous solutions to identify among them a promising carrier for further research in the field of nuclear medicine. A promising sorbent was found: oxidized NDs of the STP grade (ox-STP); conditions for the fast sorption of lutetium with it in an amount equivalent to 1.2 GBq of no-carrier-added 177Lu were determined, which corresponds to the activity used in therapy.
Publisher
Pleiades Publishing Ltd
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2 articles.
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