Formation of Various Antimicrobial Peptide Emericellipsin Isoforms in Emericellopsos alkalina under Different Cultivation Conditions

Author:

Kuvarina A. E.,Sukonnikov M. A.,Rogozhin E. A.,Serebryakova M. V.,Timofeeva A. V.,Georgieva M. L.,Sadykova V. S.

Abstract

AbstractMicrobiological screening of the target component of emericellipsin A of the Emericellopsis alkalina E101 strain has been carried out in various biotechnological systems at various pHs. The content of emericellipsin A was quantified under these conditions. It has been established that the new approved membrane-liquid cultivation method at pH 10 contributes to an increase in the yield of the main component of emericellipsin A. It has been shown that the new method of cultivating the strain E. alkalina E101 also promotes the synthesis of various isoforms of the main component of emericellipsin A. Some comparative analysis has been carried out.

Publisher

Pleiades Publishing Ltd

Subject

Applied Microbiology and Biotechnology,Biochemistry

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