Expression of the Ca2+-ATPase SERCA2a (ATP2A2) Gene and the Ryanodine Receptor (RYR2) Gene in Patients with Chronic Heart Failure

Author:

Muslimova E. F.,Rebrova T. Yu.,Kondratieva D. S.,Akhmedov Sh. D.,Afanasiev S. A.

Publisher

Pleiades Publishing Ltd

Subject

Genetics

Reference10 articles.

1. Mareev, V.Yu., Fomin, I.V., Ageev, F.T., et al., Clinical recommendations of Heart Failure Society, Russian Society of Cardiology, and Russian Scientific Medical Society of Therapists: heart failure: chronic (CHF) and acute decompensated (ADHF). Diagnostics, prophylaxis and treatment, Kardiologiya, 2018, vol. 58, no. 6, pp. 3—164. https://doi.org/10.18087/cardio.2475

2. Teplyakov, A.T., Berezikova, E.N., Shilov, S.N., et al., Assessment of the role of matrix metalloproteinase-3 gene polymorphism in the development of chronic heart failure, Ter. Arkh., 2015, vol. 87, no. 4, pp. 8—12. https://doi.org/10.17116/terarkh20158748-12

3. Rebrova, T.Y., Muslimova, E.F., Kondratieva, D.S., et al., The role of Ca2+-ATPase 2a (ATP2A2), ryanodine receptors (RYR2), and calsequestrin (CASQ2) gene polymorphisms in the development of heart failure, Russ. J. Genet., 2018, vol. 54, no. 6, pp. 604—608. https://doi.org/10.1134/S102279541806008X

4. Dulhunty, A.F., Beard, N.A., and Hanna, A.D., Regulation and dysregulation of cardiac ryanodine receptor (RyR2) open probability during diastole in health and disease, J. Gen. Physiol., 2012, vol. 140, no. 2, pp. 87—92. https://doi.org/10.1085/jgp.201210862

5. Greenberg, B., Yaroshinsky, A., Zsebo, K.M., et al., Design of a phase 2b trial of intracoronary administration of AAV1/SERCA2a in patients with advanced heart failure: the CUPID 2 trial (calcium up-regulation by percutaneous administration of gene therapy in cardiac disease phase 2b), JACC: Heart Failure, 2014, vol. 2, no. 1, pp. 84—92. https://doi.org/10.1016/j.jchf.2013.09.008

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