Modern Approaches to the Extraction and Preconcentration of Biologically Active Compounds from Plant Samples by Microextraction Methods for Their Determination by Chromatography–Mass Spectrometry

Abstract

Abstract The review considers the main trends in actively developing methods of solid-phase and liquid–liquid microextraction for the extraction, purification, and preconcentration of analytes from medicinal plants and plant materials, the use of new extractants and approaches to the preparation of samples of plant origin, and their compatibility with mass-spectrometric detection. Particular attention is paid to the analytical capabilities, advantages, and limitations of each of the approaches to extracting analytes from plant materials for the subsequent analysis of the obtained extracts by chromatography–mass spectrometry.