Insulin and Brain Gangliosides Prevent Metabolic Disorders Caused by Activation of Free Radical Reactions after Two-Vessel Ischemia–Reperfusion Injury to the Rat Forebrain
Author:
Publisher
Pleiades Publishing Ltd
Subject
Physiology,Biochemistry,Ecology, Evolution, Behavior and Systematics
Link
https://link.springer.com/content/pdf/10.1134/S0022093022010240.pdf
Reference49 articles.
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2. Huang F, Dong X, Zhang L, Zhang X, Zhao D, Bai X, Li Z (2010) GM1 and nerve growth factor modulate mitochondrial membrane potential and neurofilament light mRNA expression in cultured dorsal root ganglion and spinal cord neurons during excitotoxic glutamate exposure. J Clin Neurosci 17: 495–500. https://doi.org/10.1016/j.jocn.2009.07.112
3. Avrova NF, Victorov IV, Tyurin VA, Zakharova IO, Sokolova TV, Andreeva NA, Stelmaschuk EV, Tyurina YY, Gonchar VS (1998) Inhibition of glutamate-induced intensification of free radical reactions by gangliosides: possible role in their protective effect in rat cerebellar granule cells and brain synaptosomes. Neurochem Res 23: 945–952. https://doi.org/10.1023/a:1021076220411
4. Zakharova IO, Sokolova TV, Vlasova YA, Furaev VV, Rychkova MP, Avrova NF (2014) GM1 ganglioside activates ERK1/2 and Akt downstream of Trk tyrosine kinase and protects PC12 cells against hydrogen peroxide toxicity. Neurochem Res 39: 2262–2275. https://doi.org/10.1007/s11064-014-1428-6
5. Ramalingam M, Kim SJ (2015) Insulin exerts neuroprotective effects via Akt/Bcl-2 signaling pathways in diffrentiated SH-SY5Y cells. J Recep Signal Transduct Res 35: 1–7. https://doi.org/10.3109/10799893.2014.922576
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