Role of Titin Phosphorylation in Myocardial Stiffness Changes during Cardiomyopathies

Author:

Mikhailova G. Z.,Vikhlyantsev I. M.,Lakomkin V. L.

Publisher

Pleiades Publishing Ltd

Reference99 articles.

1. Münch J, Abdelilah-Seyfried S (2021) Sensing and Responding of Cardiomyocytes to Changes of Tissue Stiffness in the Diseased Heart. Front Cell Dev Biol 9: 642840.https://doi.org/10.3389/fcell.2021.642840

2. Linke WA (2008) Sense and stretchability: the role of titin and titin-associated proteins in myocardial stress-sensing and mechanical dysfunction. Cardiovasc Res 77(4): 637–648.https://doi.org/10.1016/j.cardiores.2007.03.029.

3. Chauveau C, Rowell J, Ferreiro A (2014) A rising titan: TTN review and mutation update. Hum Mutat 35(9): 1046–1059.https://doi.org/10.1002/humu.22611

4. Herman DS, Lam L, Taylor MR, Wang L, Teekakirikul P, Christodoulou D, Conner L, DePalma SR, McDonough B, Sparks E, Teodorescu DL, Cirino AL, Banner NR, Pennell DJ, Graw S, Merlo M, Di Lenarda A, Sinagra G, Bos JM, Ackerman MJ, Mitchell RN, Murry CE, Lakdawala NK, Ho CY, Barton PJ, Cook SA, Mestroni L, Seidman JG, Seidman CE (2012) Truncations of titin causing dilated cardiomyopathy. N Engl J Med 366(7): 619–628.https://doi.org/10.1056/NEJMoa1110186

5. Fomin A, Gärtner A, Cyganek L, Tiburcy M, Tuleta I, Wellers L, Folsche L, Hobbach AJ, von Frieling-Salewsky M, Unger A, Hucke A, Koser F, Kassner A, Sielemann K, Streckfuß-Bömeke K, Hasenfuss G, Goedel A, Laugwitz KL, Moretti A, Gummert JF, Dos Remedios CG, Reinecke H, Knöll R, van Heesch S, Hubner N, Zimmermann WH, Milting H, Linke WA (2021) Truncated titin proteins and titin haploinsufficiency are targets for functional recovery in human cardiomyopathy due to TTN mutations. Sci Transl Med 13(618): eabd3079.https://doi.org/10.1126/scitranslmed.abd3079

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