Retrovirus Restriction Factor TRIM5α: The Mechanism of Action and Prospects for Use in Gene Therapy of HIV Infection
Author:
Publisher
Pleiades Publishing Ltd
Subject
Structural Biology,Biophysics
Link
https://link.springer.com/content/pdf/10.1134/S0026893320050039.pdf
Reference78 articles.
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2. van Gent M., Sparrer K., Gack M.U. 2018. TRIM proteins and their roles in antiviral host defenses. Annu. Rev. Virol.5 (1), 385–405.
3. Stremlau M., Owens C.M., Perron M.J., Kiessling M., Autissier P., Sodroski J. 2004. The cytoplasmic body component TRIM5α restricts HIV-1 infection in Old World monkeys. Nature.427 (6977), 848–853.
4. Yap M.W., Nisole S., Lynch C., Stoye J.P. 2004. Trim5alpha protein restricts both HIV-1 and murine leukemia virus. Proc. Natl. Acad. Sci. U. S. A.101 (29), 10786–10791.
5. Keckesova Z., Ylinen L.M., Towers G.J. 2004. The human and African green monkey TRIM5alpha genes encode Ref1 and Lv1 retroviral restriction factor activities. Proc. Natl. Acad. Sci. U. S. A.101 (29), 10780–10785.
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1. The Titer of the Lentiviral Vector Encoding Chimeric TRIM5α-HRH Gene is Reduced Due to Expression of TRIM5α-HRH in Producer Cells and the Negative Effect of Ef1α Promoter;Molecular Biology;2022-01
2. Could gene therapy cure HIV?;Life Sciences;2021-07
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