Production of [124I]-iodine on an 11 MeV cyclotron

Abstract

Summary The radiohalogen, 124I, was produced by the 124Te(p,n) reaction from a glassy 124TeO2/6%Al2O3 melt on an 11 MeV proton cyclotron. A 20-degree inclined target withstands beam currents up to 20 μA with no physical damage to the substrate surface. Radioiodine was removed from the glassy melt by dry distillation techniques and trapped on cooled platinum wire. The radiochemical purity, determined by ion chromatography, shows a stable product in the iodide form over a lifetime of weeks.