Author:
Mushtaq A.,Pervez S.,Haider I.
Abstract
A simple method is described for the preparation of188Re-Lanreotide, a radiolabeled synthetic peptide derived from an analogue of somatostatin, using Lanreotide (50 μg) and stannous tartrate to which is added carrier-free188Re. The radiolabeling has been carried out with ~555 MBq (15 mCi) with a >95% labeling efficiency and no need for subsequent purification. ITLC and HPLC techniques were employed for monitoring the stability and labeling yield. Radiolabeling results in one major peak when analyzed by reverse-phase (RP) HPLC.
Subject
Physical and Theoretical Chemistry
Cited by
6 articles.
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